I’ve set up a few mesh systems for others all have been orbi however given the price now and your reliance on WiFi over wired I’d say unifi myself. I haven’t for myself as luckily our single router wap covers the whole house.
The deciding points would be throughput I believe that newer ap’s are enabled with 2.5gb Ethernet connections and have capacity for more active connections, also the ability to deploy more nodes should you find dead spots is easier. And the ease of management if you stick with a all unifi system.
I suspect you’d have to have a lot of devices to saturate a old 1gb system but given the move to more and more devices, the wfh stability needs today and a dose of future proofing it’s a reasonable call I think.
The down sides are obviously cost (though I’d argue better vfm than orbi) and having to hw the ap’s
You might also want to check what unifi switches support the 2.5gb ports
Edit:
Giving it a little more thought I’d actually go with the 1gb ap’s and just add additional ones if you found constricted zones I thank that would be significantly cheaper.