Any vets on the forum......

[Franky Four Fingers]

that wouldn’t mind me asking them a question?
TIA
FFF.

[Mr Curta]

pacifichrono was in 'nam

[pacifichrono]

Fire away!

[jukeboxs]

Or try your local vet.

[Franky Four Fingers]

Or try your local vet.

Gee, thanks I never thought of that. Thanks for the advice.


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[oldoakknives]

Not a vet but someone might be able to help or have experience of similar if they know the question. Or PM.

[Kirk280]

Do you have a problem with your slow worm?

[vortgern]

If you have a problem, if no one else can help, and if you can find them, maybe you can hire the A-Team.

[Franky Four Fingers]

Has anyone ever owned a dog with a diagnosis of mast cell tumour which totally disappeared without intervention?

[oldoakknives]

Sorry no, sounds worrying.

[manganr]

Tumours don't just disappear. Either your original diagnosis was incorrect or your current one is. Either way you should be at the vet Asap. The TZ posse cant diagnose your pets issues.

[Franky Four Fingers]

Tumours don't just disappear. Either your original diagnosis was incorrect or your current one is. Either way you should be at the vet Asap. The TZ posse cant diagnose your pets issues.

Ive been to the vets and I’m wondering why a diagnosed mast cell tumour just disappears. Everything I’ve read suggests they don’t however I’m being told they do due to histamine. Doesn’t make any sense so was just after a quick chat with someone

[ac82]

My dog had this and I seem to remember the vet saying at the time that sometimes the needle biopsy missed the cells in the tumor. After bloods and a chest x-ray the mast cells were confirmed. A new tumor was then removed and all sent to the lab for analysis which gave conclusive results of the problem.

They did say anti histamine could sometimes be used to treat so maybe that could be it?

[DavidL]

This is a completely different context but involves the same thing.
Atopic conjunctivitis (hayfever to you and me) is treated with mast cell stabilisers. These prevent the release of histamine by stabilising the mast cells, hence the name, which in turn stops the symptoms.
Tumors don't have to be malignant, they are just an overgrowth of cells bound to a surface, so yes maybe a mast cell tumor would disperse, or at least not continue to grow, as a result of something preventing the (further) effect of mediators such as histamine.
So as I see it not the because of histamine but the lack of/removal of histamine in an environment. The question is what but something with an antihistamine effect.
Have you checked your loratidine stock ;-)
And yes maybe a second opinion. All ours go to Jane Lyons who owns White Horse Vets just around the corner from you and in Calne. I like Jane and she's been pretty good to our furries.

[Franky Four Fingers]

This is a completely different context but involves the same thing.
Atopic conjunctivitis (hayfever to you and me) is treated with mast cell stabilisers. These prevent the release of histamine by stabilising the mast cells, hence the name, which in turn stops the symptoms.
Tumors don't have to be malignant, they are just an overgrowth of cells bound to a surface, so yes maybe a mast cell tumor would disperse, or at least not continue to grow, as a result of something preventing the (further) effect of mediators such as histamine.
So as I see it not the because of histamine but the lack of/removal of histamine in an environment. The question is what but something with an antihistamine effect.
Have you checked your loratidine stock ;-)
And yes maybe a second opinion. All ours go to Jane Lyons who owns White Horse Vets just around the corner from you and in Calne. I like Jane and she's been pretty good to our furries.

Thanks David.

Nothing really makes sense, I’m being told the lump can change due to histamine but from what I’ve read the histamine causes inflammation so the the body reacts to that area. Surely a cancerous lump wouldn’t completely disappear due to this though?
Shes had no treatment other than the syringe sample they took when they diagnosed a MCT. She due under the knife next Tuesday to either fully remove or take a larger sample to see how much they should remove on another visit, I’m currently cautious as I don’t want her to have any unnecessary treatment. The fact she’s also insured makes me more suspicious

[Franky Four Fingers]

My dog had this and I seem to remember the vet saying at the time that sometimes the needle biopsy missed the cells in the tumor. After bloods and a chest x-ray the mast cells were confirmed. A new tumor was then removed and all sent to the lab for analysis which gave conclusive results of the problem.

They did say anti histamine could sometimes be used to treat so maybe that could be it?

No, she’s had no antihistamine.

[DavidL]

Thanks David.

Nothing really makes sense, I’m being told the lump can change due to histamine but from what I’ve read the histamine causes inflammation so the the body reacts to that area. Surely a cancerous lump wouldn’t completely disappear due to this though?
Shes had no treatment other than the syringe sample they took when they diagnosed a MCT. She due under the knife next Tuesday to either fully remove or take a larger sample to see how much they should remove on another visit, I’m currently cautious as I don’t want her to have any unnecessary treatment. The fact she’s also insured makes me more suspicious

Some useful stuff here
https://willows.uk.net/specialist-se...40972900390625
yes the histamine is the inflammatory site so the tumor can enlarge due to inflammation including caused by biopsy.
I suppose therefore that it could resolve completely if the inflammation cause is removed but I imagine it can just as easily come back if the animal is predisposed to it.
I think if its an easily operable site I'd want it gone.

I tend to allow vets a little leeway at the expense of the insurance company if (and this rather depends on the practice) you feel they are likely to offer a little pro bono work to those who care for their animals but aren't in a situation to afford insurance or more major treatment possibly at the expense of the animals life. Also where they might explore other avenues that may not be commercially viable but may assist in their knowledge base. I realise this is a personal view and not really for this thread before someone tries to pull holes in it.

Give them a hug from us and i hope all is well.

[ac82]

Thanks David.

Nothing really makes sense, I’m being told the lump can change due to histamine but from what I’ve read the histamine causes inflammation so the the body reacts to that area. Surely a cancerous lump wouldn’t completely disappear due to this though?
Shes had no treatment other than the syringe sample they took when they diagnosed a MCT. She due under the knife next Tuesday to either fully remove or take a larger sample to see how much they should remove on another visit, I’m currently cautious as I don’t want her to have any unnecessary treatment. The fact she’s also insured makes me more suspicious

Good luck, this is the path I went down and had some success after much cost as I too was uninsured.
The vet did say at the time things would have been easier if my dog were spayed when young, she was not, apparently this can affect MCT growth