On Wednesday, the California company SpaceX will launch a mission to the International Space Station (ISS). It's something the firm has done many times before, taking cargo to the sky-high laboratory. But on this occasion, the firm will be transporting people.
It's one of those seminal moments in the history of spaceflight.
When Nasa astronauts Doug Hurley and Bob Behnken lift off atop their Falcon-9 rocket, inside their Crew Dragon capsule, it will mark the first time humans have left US territory to reach low-Earth orbit in almost nine years.
But more than that, it sees a shift to the commercialisation of human space transportation - of companies selling "taxi" rides to government and anyone else who wants to purchase the service