On the one hand: Vitamin D: A rapid review of the evidence for treatment or prevention in COVID-19
Verdict
We found no clinical evidence on vitamin D in COVID-19. There was no evidence related to vitamin D deficiency predisposing to COVID-19, nor were there studies of supplementation for preventing or treating COVID-19 (Search date upto 4th of April 2020, clinicaltrials.gov searched upto on 23rd April).
There is some evidence that daily vitamin D3 supplementation over weeks to months may prevent other acute respiratory infections, particularly in people with low or very low vitamin D status. This evidence has limitations, including heterogeneity in study populations, interventions, and definitions of respiratory infections that include upper and lower respiratory tract involvement...
On the other: UK public health bodies reviewing vitamin D's effects on coronavirus
Public health officials are urgently reviewing the potential ability of vitamin D to reduce the risk of coronavirus.
It comes amid growing concern over the disproportionate number of black, Asian and minority ethnic people contracting and dying from the disease, including a reported 94% of all doctors killed by the virus.
A delayed Public Health England review into the reasons why BAME people are disproportionately affected, which pointed to historical racism, did not review the role of diet and vitamin D.
The Scientific Advisory Committee on Nutrition (SACN) began this work last month and is considering recent evidence on vitamin D and acute respiratory tract infection in the general population. Evidence will be considered on specific population groups, including those of different ages and BAME groups.
In a parallel development, the National Institute for Health and Care Excellence (Nice) is conducting a “rapid” evidence review on vitamin D “in the context of Covid-19” with support from Public Health England (PHE).
It is understood the reviews will be published in the coming weeks. The Nice review may be used alongside other available information, such as specific patient circumstances, to inform individual healthcare decisions.
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UK vitamin D advice is focused on musculoskeletal health conditions such as rickets and there are fears that its effect on general immune systems has been overlooked...
Can we agree on a verdict of 'Not Proven'?