I listened to the qb1 against the muso and found the qb lacking in comparison in a larger space. It still sounded great but for the difference (and I suspect you could get the muso within your budget now) I’d go for the muso over the qb1. The qb1 is limited by its size and for a smaller study/office space would probably be ideal.
I haven’t heard the qb2 or the second gen muso so can’t offer any insight.