Everything, just about. So much so that I find it amazing that so many work so well. Here are some factors.
1. Temperature
2. Gravity (e.g., orientation)
3. Condition of movement
-- structural faults, such as nicks in pivots, ill shaped wheels, and worn bearings
-- oil condition and distribution
-- dirt
4. Magnetic fields
5. Shocks
6. Fit of parts (e.g., an hour hand rubbing something)
7. Pixies (misc / improbable collapse of the wave packet)
Best wishes,
Bob