Yes! As long as it's got some thickness to it - something appropriate to the lug size and head weight of watches like the DN and the PRS-50. One of the downsides of the original O7 silicone strap was that it was too floppy.
Is it possible to get a non-tapered version? I can see where one would want a 24 to taper to 20 or 22 at the buckle, but I'd prefer 20 and 22mm straps to not taper.
Is the manufacturer offering silicone only, or is urethane an option? Urethane is more comfortable IMO and the original Omega Isofrane was a type of closed-microcellular urethane foam.